Diane M Simeone Medical School, Surgery - General Surgery

Diane M Simeone

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Contemporary Management of Nonfunctioning Pancreatic Neuroendocrine Tumors

Rebecca M. Minter; Diane M. Simeone

(Profiled Authors: Rebecca M Minter; Diane M Simeone)

Journal of Gastrointestinal Surgery. 2012;16(2):435-446.

Abstract

Background: This article reviews the current literature and recommendations pertaining to the management of nonfunctioning pancreatic neuroendocrine tumors. Discussion: In recent years the detection of nonfunctioning pancreatic neuroendocrine tumors has increased coincident with the increased use of cross-sectional imaging and is now thought to represent 2-10% of all pancreatic tumors. Improved understanding of the biology and behavior of these heterogeneous tumors is needed to guide therapy. The present review discusses diagnostics, therapeutics including emerging molecular analytics, and surveillance recommendations. © 2011 The Society for Surgery of the Alimentary Tract.


PMID: 22009463    

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